MoS2 Nanoparticles as Electrocatalytic Labels in Magneto-Immunoassays
- Daniel Bouša, Carmen C. Mayorga-Martinez, Vlastimil Mazánek, Zdeněk Sofer, Kristyna Bousova, Martin Pumera*
Ability to detect biomolecules with a simple and cost-effective approach has been very demanding in today's medicine. The nanoparticles and two-dimensional materials have been extensively used within this field in devices with high selectivity and sensitivity. Here, we report the use of MoS2 nanoparticles (MoS2 NPs) as a signal-enhancing label in a standard immunoassay test. MoS2 NPs were prepared by a bipolar electrochemistry method. The current response during the hydrogen evolution reaction catalyzed by MoS2 was measured. This current was directly proportional to the amount of the MoS2 NPs and thus also to the concentration of desired protein. The immunoassay containing the MoS2 NPs displays extraordinary low limit of detection (1.94 pg mL(-1)), good selectivity, and reproducibility. This MoS2 NP detection system could have profound implication for analytical applications.
Impurities in graphene/PLA 3D-printing filaments dramatically influence the electrochemical properties of the devices
Flexible Pt/Graphene Foil Containing only 6.6 wt % of Pt has a Comparable Hydrogen Evolution Reaction Performance to Platinum Metal