Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides

A microfluidic analytical system for the separation and detection of organic peroxides. based on a microchip capillary electrophoresis device with an integrated amperometric detector. was developed. The new microsystem relies on the reductive detection of both organic acid peroxides and hydroperoxides at -700 mV (vs. Ag wire/AgCl). Factors influencing the separation and detection processes were examined and optimized, The integrated microsystem offers rapid measurements (within 130 s) of these organic-peroxide compounds, down to micromolar levels. A highly stable response for repetitive injections (RSD 0.35-3.12% n = 12) reflects the negligible electrode passivation. Such a "lab-on-a-chip" device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring, (C) 2002 Elsevier Science B.V. All rights reserved.